Compound Summary
Compound Information
153587-01-0
Compound Name: | 153587-01-0 |
Compound CID: | 4552 |
Synonyms: | 153587-01-0 NS-1619 NS 1619 NS1619 1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzodimidazol-2(3H)-one More... |
Iupac Name: | 3-[2-hydroxy-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-1H-benzimidazol-2-one |
InChI: | InChI=1S/C15H8F6N2O2/c16-14(17,18)7-1-3-10-9(5-7)22-13(25)23(10)11-6-8(15(19,20)21)2-4-12(11)24/h1-6,24H,(H,22,25) |
InChIKey: | YLFMCMWKHSDUCT-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC2=C(C=C1C(F)(F)F)NC(=O)N2C3=C(C=CC(=C3)C(F)(F)F)O |
Isomeric Smiles: | C1=CC2=C(C=C1C(F)(F)F)NC(=O)N2C3=C(C=CC(=C3)C(F)(F)F)O |
Molecular Weight: | 362.23 |
Molecular Formula: | C15H8F6N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
153587-01-0
Molecular Weight: | 362.23 |
Molecular Formula: | C15H8F6N2O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 25 |
Complexity: | 523 |
Synonyms
153587-01-0
| 153587-01-0 | 153587-01-0 |
|---|---|
153587-01-0 |
NS-1619 |
NS 1619 |
NS1619 |
1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzodimidazol-2(3H)-one |
CHEMBL384903 |
C15H8F6N2O2 |
1,3-Dihydro-1-2-hydroxy-5-(trifluoromethyl)phenyl-5-(trifluoromethyl)-2H-benzimidazol-2-one |
CHEBI:34879 |
1-(2-Hydroxy-5-trifluoromethylphenyl)-5-trifluoromethyl-2(3H)-benzimidazolone |
MFCD00928190 |
3-2-hydroxy-5-(trifluoromethyl)phenyl-6-(trifluoromethyl)-1H-benzimidazol-2-one |
1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzodimid azol-2(3H)-one |
1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1,3-dihydro-2H-benzodimidazol-2-one |
1,3-dihydro-1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-2H-Benzimidazol-2-one |
1-2-hydroxy-5-(trifluoromethyl)phenyl-5-(trifluoromethyl)-1,3-dihydro-2h-benzimidazol-2-one |
ACMC-20agb2 |
NS 1619, powder |
Lopac-N-170 |
Lopac0_000892 |
BSPBio_001425 |
KBioGR_000145 |
KBioSS_000145 |
MLS002172485 |
GTPL4272 |
SCHEMBL2820871 |
BCBcMAP01_000241 |
KBio2_000145 |
KBio2_002713 |
KBio2_005281 |
KBio3_000289 |
KBio3_000290 |
DTXSID80165363 |
Bio2_000145 |
Bio2_000625 |
HMS1361H07 |
HMS1791H07 |
HMS1989H07 |
HMS2233C07 |
HMS3262D06 |
HMS3374I04 |
HMS3402H07 |
AMY36458 |
BCP23926 |
EX-A3548 |
ZINC9225331 |
Tox21_500892 |
BDBM50347497 |
KC-127 |
AKOS016007330 |
CCG-204974 |
CS-3613 |
LP00892 |
SDCCGSBI-0050867.P002 |
IDI1_033895 |
NCGC00015720-01 |
NCGC00015720-02 |
NCGC00015720-03 |
NCGC00015720-04 |
NCGC00015720-05 |
NCGC00015720-06 |
NCGC00015720-07 |
NCGC00015720-11 |
NCGC00094210-01 |
NCGC00094210-02 |
NCGC00094210-03 |
NCGC00094210-04 |
NCGC00261577-01 |
2H-Benzimidazol-2-one, 1,3-dihydro-1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)- |
2H-Benzimidazol-2-one,1,3-dihydro-1-2-hydroxy-5-(trifluoromethyl)phenyl-5-(trifluoromethyl)- |
AS-55902 |
HY-12496 |
SMR001254108 |
DB-043194 |
B7502 |
EU-0100892 |
FT-0643507 |
X6428 |
A809445 |
SR-01000075337 |
J-009032 |
SR-01000075337-1 |
BRD-K54210043-001-02-0 |
Q27088047 |
1-(2-Hydroxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-one |
5-trifluoromethyl-2,3-dihydro-1-(5-trifluoromethyl-2-hydroxyphenyl)-1H-2-oxo-benzimidazole |
1,3-Dihydro-1-2-hydroxy-5-(trifluo romethyl)phenyl-5-(trifluoromethyl)-2H-benzimidazol-2-one |
1-2-hydroxy-5-(trifluoromethyl)phenyl-5-(trifluoromethyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one |
Experimental Data
153587-01-0
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -16 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
153587-01-0
Statistics Data
153587-01-0
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -16 | 1 | 1 |
Statistics Data Visualization
153587-01-0
