Compound Summary
Compound Information
133550-30-8
Compound Name: | 133550-30-8 |
Compound CID: | 5328779 |
Synonyms: | 133550-30-8 AG-490 Tyrphostin B42 AG 490 Tyrphostin AG 490 More... |
Iupac Name: | (E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide |
InChI: | InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+ |
InChIKey: | TUCIOBMMDDOEMM-RIYZIHGNSA-N |
Canonical Smiles: | C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N |
Isomeric Smiles: | C1=CC=C(C=C1)CNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N |
Molecular Weight: | 294.3 |
Molecular Formula: | C17H14N2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
133550-30-8
Molecular Weight: | 294.3 |
Molecular Formula: | C17H14N2O3 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 22 |
Complexity: | 460 |
Synonyms
133550-30-8
| 133550-30-8 | 133550-30-8 |
|---|---|
133550-30-8 |
AG-490 |
Tyrphostin B42 |
AG 490 |
Tyrphostin AG 490 |
AG490 |
(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide |
Tyrphostin AG490 |
tyrphostin AG-490 |
AG-490 (Tyrphostin B42) |
(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide |
N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide |
alpha-Cyano-(3,4-dihydroxy)-N-benzylcinnamide |
134036-52-5 |
(2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide |
CHEMBL56543 |
SMR001230665 |
SR-01000076153 |
MFCD00236452 |
n-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide |
Tyrphostin,AG490 |
xy-phenyl)-acrylamide |
Tocris-0414 |
Tyrphostin deriv. 42 |
BiomolKI_000025 |
Lopac-T-3434 |
BiomolKI2_000033 |
Tyrphostin AG 490, solid |
Lopac0_001166 |
SCHEMBL93682 |
BMK1-D1 |
BSPBio_001396 |
cc-365 |
MLS002153172 |
MLS006011256 |
BDBM4313 |
GTPL5916 |
DTXSID5040960 |
AOB6474 |
EX-A118 |
EX-A464 |
CHEBI:131968 |
BCPP000424 |
HMS1361F18 |
HMS1791F18 |
HMS1989F18 |
HMS2231N13 |
HMS3229M15 |
HMS3402F18 |
HMS3414G11 |
HMS3678G11 |
ZINC2557947 |
EI-272 |
s1143 |
SBB063097 |
ZINC02557947 |
(2E)-2-CYANO-3-(3,4-DIHYDROXYPHENYL)-N-(PHENYLMETHYL)-2-PROPENAMIDE |
AKOS015888137 |
BCP9000246 |
CCG-100629 |
LP01166 |
QC-8950 |
SDCCGSBI-0051133.P003 |
IDI1_033866 |
SMP2_000154 |
NCGC00016014-01 |
NCGC00016014-02 |
NCGC00016014-03 |
NCGC00016014-04 |
NCGC00016014-05 |
NCGC00016014-06 |
NCGC00016014-07 |
NCGC00016014-09 |
NCGC00016014-10 |
NCGC00024576-01 |
NCGC00024576-02 |
NCGC00024576-03 |
NCGC00024576-04 |
NCGC00024576-05 |
NCGC00024576-06 |
BS-15205 |
(E)-N-Benzyl-2-cyano-3-(3,4-dihydro |
EU-0101166 |
SW219272-1 |
T2962 |
X7479 |
EC-000.2082 |
C72336 |
T 3434 |
alpha-Cyano-(3,4-dihydroxy)-N-benzylcinnamamide |
J-500741 |
SR-01000076153-1 |
SR-01000076153-3 |
BRD-K47105409-001-05-3 |
Q27074341 |
(2E)-3-(3,4-dihydroxyphenyl)-2-cyano-N-benzylprop-2-enamide |
(E)-N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamideAG 490 |
2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)- |
(E)-2-CYANO-3-(3,4-DIHYDROPHENYL)-N-(PHENYLMETHYL)-2-PROPENAMIDE |
Experimental Data
133550-30-8
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 300 | umol/L | 17.5 | S | Oregon-R | 22363408 | Active | ||||||
| Caenorhabditis elegans | 33 | umol/L | 6 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
133550-30-8
Statistics Data
133550-30-8
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 6 | 1 | 1 | |
| Drosophila melanogaster | 17.5 | 1 | 1 |
Statistics Data Visualization
133550-30-8
