Compound Summary
Compound Information
Rilmenidine
Compound Name: | Rilmenidine |
Compound CID: | 68712 |
Synonyms: | Rilmenidine 54187-04-1 Hyperium Oxaminozoline N-(Dicyclopropylmethyl)-4,5-dihydrooxazol-2-amine More... |
Iupac Name: | N-(dicyclopropylmethyl)-4,5-dihydro-1,3-oxazol-2-amine |
InChI: | InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12) |
InChIKey: | CQXADFVORZEARL-UHFFFAOYSA-N |
Canonical Smiles: | C1CC1C(C2CC2)NC3=NCCO3 |
Isomeric Smiles: | C1CC1C(C2CC2)NC3=NCCO3 |
Molecular Weight: | 180.25 |
Molecular Formula: | C10H16N2O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Rilmenidine
Molecular Weight: | 180.25 |
Molecular Formula: | C10H16N2O |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 13 |
Complexity: | 219 |
Synonyms
Rilmenidine
| Rilmenidine | Rilmenidine |
|---|---|
Rilmenidine |
54187-04-1 |
Hyperium |
Oxaminozoline |
N-(Dicyclopropylmethyl)-4,5-dihydrooxazol-2-amine |
Rilmenidine INN |
N-(Dicyclopropylmethyl)-4,5-dihydro-1,3-oxazol-2-amine |
Rilmenidia Spanish |
Rilmenidinum Latin |
2-Oxazolamine, N-(dicyclopropylmethyl)-4,5-dihydro- |
CHEBI:8862 |
Oxazolidine, 2-((dicyclopropylmethyl)imino)- |
P67IM25ID8 |
Rilmenidine (INN) |
NSC664312 |
NCGC00015884-09 |
CAS-54187-04-1 |
NSC 664312; Oxaminozoline; Rilmenidene;S 3341 |
SR-01000002992 |
EINECS 259-021-0 |
S 3341 |
BRN 1211287 |
UNII-P67IM25ID8 |
Hyperium (TN) |
Methylamine, 1,1-dicyclopropyl-N-(2-oxazolinyl)- |
2-Oxazolamine, 4,5-dihydro-N-(dicyclopropylmethyl)- |
Tocris-0790 |
ARSENICTRIFLUORIDE |
Lopac-R-134 |
RILMENIDINE MI |
Prestwick0_000982 |
Prestwick1_000982 |
Prestwick2_000982 |
Prestwick3_000982 |
Lopac0_001104 |
BSPBio_001043 |
RILMENIDINE WHO-DD |
SCHEMBL114420 |
SPBio_002944 |
BPBio1_001149 |
CHEMBL289480 |
ZINC9708 |
DTXSID3045194 |
HMS2089G15 |
HMS3263M10 |
Tox21_110254 |
Tox21_501104 |
BDBM50070328 |
MFCD00865924 |
2-(dicyclopropylmethylamino) oxazoline |
AKOS006273431 |
Tox21_110254_1 |
AB07513 |
CCG-205180 |
DB11738 |
LP01104 |
NSC-664312 |
SDCCGSBI-0051073.P002 |
NCGC00015884-01 |
NCGC00015884-02 |
NCGC00015884-03 |
NCGC00015884-04 |
NCGC00015884-05 |
NCGC00015884-06 |
NCGC00015884-07 |
NCGC00015884-08 |
NCGC00015884-10 |
NCGC00015884-11 |
NCGC00015884-13 |
NCGC00015884-19 |
NCGC00021689-02 |
NCGC00021689-04 |
NCGC00021689-05 |
NCGC00021689-06 |
NCGC00261789-01 |
(N-dicyclopropylmethyl)-amino-2-oxazoline |
NCI60_022181 |
SY267932 |
DB-052512 |
HY-100490 |
AB00514648 |
CS-0019423 |
EU-0101104 |
FT-0630668 |
R-134 |
D08482 |
AB00513728-09 |
EN300-8092697 |
187R041 |
A830020 |
L001230 |
Q967973 |
N-(Dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine; |
SR-01000002992-3 |
SR-01000002992-4 |
W-105661 |
N-(dicyclopropylmethyl)-4,5-dihydrooxazol-3-ium-2-amine |
N-(Dicyclopropylmethyl)-N-(4,5-dihydro-1,3-oxazol-2-yl)amine |
Experimental Data
Rilmenidine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 150 | umol/L | 21.85 | 24.72 | 13.14 | 29 | 31 | 0.07 | S | N2 | 36670049 | Active | |
| Caenorhabditis elegans | 300 | umol/L | 21.85 | 23.83 | 9.06 | 29 | 33 | 0.14 | S | N2 | 36670049 | Active | |
| Caenorhabditis elegans | 250 | umol/L | 26.41 | 27.48 | 4.05 | 33 | 36 | 0.09 | S | N2 | 36670049 | Active | |
| Caenorhabditis elegans | 200 | umol/L | 21.85 | 26.02 | 19.08 | 29 | 33 | 0.14 | S | N2 | 36670049 | Active | |
| Caenorhabditis elegans | 400 | umol/L | 21.85 | 21.54 | -1.48 | 29 | 30 | 0.03 | NS | N2 | 36670049 | Inactive | |
| Caenorhabditis elegans | 200 | umol/L | 26.41 | 25.58 | -3.14 | 33 | 32 | -0.03 | NS | N2 | 36670049 | Inactive | |
| Caenorhabditis elegans | 150 | umol/L | 26.41 | 27.98 | 5.94 | 33 | 35 | 0.06 | S | N2 | 36670049 | Active | |
| Caenorhabditis elegans | 100 | umol/L | 21.85 | 25.44 | 16.43 | 29 | 33 | 0.14 | S | N2 | 36670049 | Active | |
| Caenorhabditis elegans | 100 | umol/L | 26.41 | 28.31 | 7.19 | 33 | 33 | 0 | S | N2 | 36670049 | Active |
Experimental Data Visualization
Rilmenidine
Statistics Data
Rilmenidine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 19.08 | 0.14 | 1 | 9 |
Statistics Data Visualization
Rilmenidine
