Compound Summary
Compound Information
Tropisetron hydrochloride
Compound Name: | Tropisetron hydrochloride |
Compound CID: | 9818540 |
Synonyms: | Tropisetron hydrochloride 105826-92-4 3-Tropanyl-indole-3-carboxylate hydrochloride SDZ-ICS-930 SDZ-ICS-930 (free base) More... |
Iupac Name: | (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 1H-indole-3-carboxylate;hydrochloride |
InChI: | InChI=1S/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,18H,6-9H2,1H3;1H |
InChIKey: | XIEGSJAEZIGKSA-UHFFFAOYSA-N |
Canonical Smiles: | CN1C2CCC1CC(C2)OC(=O)C3=CNC4=CC=CC=C43.Cl |
Isomeric Smiles: | CN1C2CCC1CC(C2)OC(=O)C3=CNC4=CC=CC=C43.Cl |
Molecular Weight: | 320.8 |
Molecular Formula: | C17H21ClN2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tropisetron hydrochloride
Molecular Weight: | 320.8 |
Molecular Formula: | C17H21ClN2O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 22 |
Complexity: | 400 |
Synonyms
Tropisetron hydrochloride
| Tropisetron hydrochloride | Tropisetron hydrochloride |
|---|---|
Tropisetron hydrochloride |
105826-92-4 |
3-Tropanyl-indole-3-carboxylate hydrochloride |
SDZ-ICS-930 |
SDZ-ICS-930 (free base) |
ICS 205-930 |
3-Tropanylindole-3-carboxylate hydrochloride |
MLS001148140 |
CHEMBL554182 |
SCHEMBL6273985 |
(3-endo)-8-Methyl-8-azabicyclo3.2.1oct-3-yl 1H-Indole-3-carboxylate Hydrochloride |
Pharmakon1600-01502344 |
BCP07756 |
Tox21_501253 |
AC-789 |
CT0261 |
NSC759842 |
AKOS015951162 |
CCG-213827 |
ICS-205,930; Navoban; Tropisetron |
LP01253 |
MCULE-1494492129 |
NSC-759842 |
(8-methyl-8-azabicyclo3.2.1octan-3-yl) 1H-indole-3-carboxylate hydrochloride |
NCGC00094493-01 |
NCGC00261938-01 |
SMR000653456 |
DB-040658 |
EU-0101253 |
FT-0630963 |
T-104 |
T2743 |
A801326 |
SR-01000075588 |
J-500370 |
SR-01000075588-1 |
Tropisetron monohydrochloride, solid, >=98% (HPLC) |
Tropisetron hydrochloride, European Pharmacopoeia (EP) Reference Standard |
(1R,5S)-8-methyl-8-azabicyclo3.2.1octan-3-yl 1H-indole-3-carboxylate hydrochloride |
1H-indole-3-carboxylic acid (8-methyl-8-azabicyclo3.2.1octan-3-yl) ester hydrochloride |
8-methyl-8-azabicyclo3.2.1octan-3-yl 1H-indole-3-carboxylate hydrochloride |
Experimental Data
Tropisetron hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 0 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tropisetron hydrochloride
Statistics Data
Tropisetron hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0 | 1 | 1 |
Statistics Data Visualization
Tropisetron hydrochloride
