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Compound Summary

2-ketoglutaric acid

Compound Information

2-ketoglutaric acid

Compound Name:	2-ketoglutaric acid
Compound CID:	51
Synonyms:	2-ketoglutaric acid 2-Oxopentanedioic acid 328-50-7 alpha-ketoglutaric acid 2-oxoglutaric acid More...
Iupac Name:	2-oxopentanedioic acid
InChI:	InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChIKey:	KPGXRSRHYNQIFN-UHFFFAOYSA-N
Canonical Smiles:	C(CC(=O)O)C(=O)C(=O)O
Isomeric Smiles:	C(CC(=O)O)C(=O)C(=O)O
Molecular Weight:	146.1
Molecular Formula:	C5H6O5

Compound Structure

2D Structure:

3D Structure:

Computed Properties

2-ketoglutaric acid

Molecular Weight:	146.1
Molecular Formula:	C5H6O5
Hydrogen Bond Donor Count:	2
Hydrogen Bond Acceptor Count:	5
Rotatable Bond Count:	4
Heavy Atom Count:	10
Complexity:	171

Synonyms

2-ketoglutaric acid

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2-ketoglutaric acid	2-ketoglutaric acid
.alpha.-Ketoglutaric acid	CHEMBL1686
11044-EP2269610A2	11044-EP2277848A1
11044-EP2289510A1	11044-EP2316457A1

Showing 1 to 3 of 70 entries

Experimental Data

2-ketoglutaric acid

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Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	Gender	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	8.000000000000000	mM	14.000000000000000	20.700000000000000	0.480000000000000				S	N2		26190651	Active
Caenorhabditis elegans	8.000000000000000	mM	15.700000000000000	21.500000000000000	0.370000000000000				S	N2		26190651	Active
Caenorhabditis elegans	8.000000000000000	mM	18.000000000000000	23.000000000000000	0.280000000000000				S	N2		31820364	Active
Caenorhabditis elegans	8.000000000000000	mM	14.000000000000000	20.700000000000000	47.900000000000000				S	N2		24828042	Active
Caenorhabditis elegans	8.000000000000000	mM	21.500000000000000	14.600000000000000	14.600000000000000				S	N2		24828042	Active
Caenorhabditis elegans	8.000000000000000	mM	16.800000000000000	22.400000000000000	32.000000000000000				S	N2		24828042	Active
Caenorhabditis elegans	8.000000000000000	mM	15.700000000000000	21.600000000000000	32.700000000000000				S	N2		24828042	Active
Caenorhabditis elegans	8.000000000000000	mM	18.400000000000000	24.600000000000000	33.400000000000000				S	N2		24828042	Active
Caenorhabditis elegans	8.000000000000000	mM	15.600000000000000	26.300000000000000	68.800000000000000				S	N2		24828042	Active
Caenorhabditis elegans	8.000000000000000	mM	13.600000000000000	20.700000000000000	51.800000000000000				S	N2		24828042	Active

Showing 1 to 10 of 21 entries

Experimental Data Visualization

2-ketoglutaric acid

Statistics Data

2-ketoglutaric acid

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Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	69.800000000000000		3	19
Drosophila melanogaster	7.740000000000000		1	2

Showing 1 to 2 of 2 entries

Statistics Data Visualization

2-ketoglutaric acid