Compound Summary
TPCK
Compound Information
TPCK
Compound Name: | TPCK |
Compound CID: | 439647 |
Synonyms: | TPCK 402-71-1 N-Tosyl-L-phenylalanyl chloromethyl ketone N-Tosyl-L-phenylalanine chloromethyl ketone TOSYLPHENYLALANYL CHLOROMETHYL KETONE More... |
Iupac Name: | N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-4-methylbenzenesulfonamide |
InChI: | InChI=1S/C17H18ClNO3S/c1-13-7-9-15(10-8-13)23(21,22)19-16(17(20)12-18)11-14-5-3-2-4-6-14/h2-10,16,19H,11-12H2,1H3/t16-/m0/s1 |
InChIKey: | MQUQNUAYKLCRME-INIZCTEOSA-N |
Canonical Smiles: | CC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CC=CC=C2)C(=O)CCl |
Isomeric Smiles: | CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=CC=C2)C(=O)CCl |
Molecular Weight: | 351.8 |
Molecular Formula: | C17H18ClNO3S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
TPCK
Molecular Weight: | 351.8 |
Molecular Formula: | C17H18ClNO3S |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 23 |
Complexity: | 475 |
Synonyms
TPCK
| TPCK | TPCK |
|---|---|
TPCK |
402-71-1 |
N-Tosyl-L-phenylalanyl chloromethyl ketone |
N-Tosyl-L-phenylalanine chloromethyl ketone |
TOSYLPHENYLALANYL CHLOROMETHYL KETONE |
Tos-Phe-CH2Cl |
N-p-Tosyl-L-phenylalanine chloromethyl ketone |
L-1-Tosylamido-2-phenylethyl chloromethyl ketone |
(S)-N-(4-Chloro-3-oxo-1-phenylbutan-2-yl)-4-methylbenzenesulfonamide |
l-N-(alpha-(Chloroacetyl)phenethyl)-p-toluenesulfonamide |
N-(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl-4-methylbenzenesulfonamide |
CHEMBL60718 |
UNII-P598716LJT |
MLS000028752 |
CHEBI:9642 |
P598716LJT |
Benzenesulfonamide,N-(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl-4-methyl- |
SMR000058518 |
p-Toluenesulfonamide, N-(alpha-(chloroacetyl)phenethyl)-, (-)- |
Benzenesulfonamide, N-(3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl-, (S)- |
N-(p-Toluenesulfonyl)-L-phenylalanine chloromethyl ketone |
Benzenesulfonamide, N-3-chloro-2-oxo-1-(phenylmethyl)propyl-4-methyl-, (S)- |
EINECS 206-954-6 |
Tosylphenylalanyl chloromethyl ketone, (L)- |
BRN 2895215 |
L-Chloromethyl (2-phenyl-1-(p-toluenesulphonylamino)ethyl) ketone |
Opera_ID_1094 |
Lopac-T-4376 |
Tosyl-Phe-CMK (TPCK) |
tosylphenylalanylchloromethane |
Lopac0_001157 |
BSPBio_001541 |
KBioGR_000261 |
KBioSS_000261 |
L-1-p-Tosylamino-2-phenylethyl chloromethyl ketone |
MLS001076075 |
MLS006010721 |
SCHEMBL927265 |
cid_439647 |
Tosyl-L-phenylalanylchloromethane |
KBio2_000261 |
KBio2_002829 |
KBio2_005397 |
KBio3_000521 |
KBio3_000522 |
BRD5988 |
DTXSID60883376 |
Benzenesulfonamide, N-((1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl- |
Bio2_000261 |
Bio2_000741 |
HMS1361N03 |
HMS1791N03 |
HMS1989N03 |
HMS3263H15 |
HMS3402N03 |
ZINC901254 |
BRD-5988 |
Tox21_501157 |
7793AH |
BDBM50085363 |
CAS329306 |
MFCD00000935 |
NSC727365 |
PI-122 |
CCG-205231 |
LP01157 |
NSC 727365 |
NSC-727365 |
SDCCGSBI-0051124.P003 |
IDI1_034011 |
NCGC00016020-01 |
NCGC00094419-01 |
NCGC00094419-02 |
NCGC00094419-03 |
NCGC00094419-04 |
NCGC00094419-05 |
NCGC00094419-06 |
NCGC00094419-07 |
NCGC00261842-01 |
AS-35326 |
p-Tosyl-L-phenylalanine chloromethylketone |
EU-0101157 |
N-P-tosyl-L-phenylalanyl chloromethyl ketone |
T2810 |
C02088 |
L-1-Tosylamido-2-phenylethylchloromethyl ketone |
T 4376 |
A873400 |
SR-01000076157 |
Q7827912 |
SR-01000076157-1 |
BRD-K07055988-001-02-4 |
L-1-TOSYLAMIDE-2-PHENYLETHYL-CHLOROMETHYL KETONE |
l-N-(.alpha.-(Chloroacetyl)phenethyl)-p-toluenesulfonamide |
(3S)-3-(p-Toluenesulfonyl)amino-1-chloro-4-phenyl-2-butanone |
(S)-N-(4-Chloro-3-oxo-1-phenyl-2-butyl)-p-toluenesulfonamide |
L-(Toluene-4-sulfonamido-2-phenyl)ethyl chloromethyl ketone |
p-Toluenesulfonamide, N-(.alpha.-(chloroacetyl)phenethyl)-, (-)- |
N-(1S)-1-benzyl-3-chloro-2-oxo-propyl-4-methyl-benzenesulfonamide |
N-p-Tosyl-L-phenylalanine chloromethyl ketone, >=97% (TLC), powder |
Experimental Data
TPCK
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 2.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
TPCK
Statistics Data
TPCK
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 2.000000000000000 | 1 | 1 |
Statistics Data Visualization
TPCK
