Compound Summary
riluzole
Compound Information
riluzole
Compound Name: | riluzole |
Compound CID: | 5070 |
Synonyms: | riluzole 1744-22-5 Rilutek 2-Amino-6-(trifluoromethoxy)benzothiazole 6-(trifluoromethoxy)benzodthiazol-2-amine More... |
Iupac Name: | 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine |
InChI: | InChI=1S/C8H5F3N2OS/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5/h1-3H,(H2,12,13) |
InChIKey: | FTALBRSUTCGOEG-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N |
Isomeric Smiles: | C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N |
Molecular Weight: | 234.2 |
Molecular Formula: | C8H5F3N2OS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
riluzole
Molecular Weight: | 234.2 |
Molecular Formula: | C8H5F3N2OS |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 15 |
Complexity: | 238 |
Synonyms
riluzole
| riluzole | riluzole |
|---|---|
riluzole |
1744-22-5 |
Rilutek |
2-Amino-6-(trifluoromethoxy)benzothiazole |
6-(trifluoromethoxy)benzodthiazol-2-amine |
6-(trifluoromethoxy)-1,3-benzothiazol-2-amine |
RP-54274 |
2-amino-6-trifluoromethoxybenzothiazole |
2-amino-6-(trifluoromethoxy)benzodthiazole |
2-Benzothiazolamine, 6-(trifluoromethoxy)- |
PK-26124 |
RP 54274 |
C8H5F3N2OS |
UNII-7LJ087RS6F |
Riluzole (Rilutek) |
Amino-2 trifluoromethoxy-6 benzothiazole |
MLS000069369 |
6-Trifluoromethoxy-benzothiazol-2-ylamine |
2-Benzothiazolamine,6-(trifluoromethoxy)- |
2-Amino-6-(trifluoromethoxy)-benzothiazole |
CHEMBL744 |
SMR000058231 |
7LJ087RS6F |
CHEBI:8863 |
Riluzol |
2-amino-6-(trifluoromethoxy)-1,3-benzothiazole |
BENZOTHIAZOLE, 2-AMINO-6-TRIFLUOROMETHOXY- |
MFCD00210213 |
NCGC00015882-09 |
Riluzolum |
Riluzol INN-Spanish |
Riluzolum INN-Latin |
DSSTox_CID_25192 |
DSSTox_RID_80739 |
DSSTox_GSID_45192 |
Rilutek (TN) |
CAS-1744-22-5 |
6-(trifluoromethoxy)benzothiazole-2-ylamine |
Amino-2 trifluoromethoxy-6 benzothiazole French |
2-amino-6-(trifluoromethoxyl)benzothiazole |
Riluzole, solid |
Riluzole USAN:USP:INN:BAN |
Riluzole- Bio-X |
BF-37 |
ALBB-006046 |
Prestwick-03A08 |
6-(trifluoromethoxy)-2-benzothiazolamine |
Tocris-0768 |
PK 26124 |
6-trifluoromethoxybenzothiazole-2-yl-amine |
Opera_ID_548 |
Lopac-R-116 |
Riluzole-13C-15N2 |
Prestwick0_000167 |
Prestwick1_000167 |
Prestwick2_000167 |
Prestwick3_000167 |
Spectrum2_000550 |
Biomol-NT_000245 |
cid_5070 |
Riluzole (JAN/USP/INN) |
Lopac0_001064 |
SCHEMBL78905 |
BSPBio_000033 |
BIDD:GT0055 |
SPBio_000599 |
SPBio_001954 |
ACMC-209e89 |
BPBio1_000037 |
BPBio1_000837 |
GTPL2326 |
ZINC6481 |
DTXSID3045192 |
BDBM30705 |
Bio1_000416 |
Bio1_000905 |
Bio1_001394 |
HMS1773G08 |
HMS2089O19 |
HMS2094G07 |
HMS2233E14 |
HMS3263E10 |
HMS3371A09 |
HMS3657E13 |
Pharmakon1600-01505348 |
AMY14166 |
BCP02142 |
BHV-0223 |
HY-B0211 |
Riluzole - CAS 1744-22-5 |
Tiglutik (thickened oral suspension) |
Tox21_110252 |
Tox21_501064 |
AC-730 |
BBL013272 |
CCG-39528 |
NSC753433 |
NSC759823 |
s1614 |
SBB012436 |
STK503686 |
AKOS000265071 |
Tox21_110252_1 |
DB00740 |
KS-5231 |
LP01064 |
MCULE-9362288181 |
NSC 753433 |
NSC 759823 |
NSC-753433 |
NSC-759823 |
SDCCGSBI-0051034.P003 |
2-amino-6-trifluoromethoxy-benzothiazole |
6-(trifluoromethoxy)benzothiazol-2-amine |
6-trifluoromethoxy-2-amino-benzothiazole |
NCGC00015882-01 |
NCGC00015882-02 |
NCGC00015882-03 |
NCGC00015882-04 |
NCGC00015882-05 |
NCGC00015882-06 |
NCGC00015882-07 |
NCGC00015882-08 |
NCGC00015882-10 |
NCGC00015882-11 |
NCGC00015882-12 |
NCGC00015882-13 |
NCGC00015882-15 |
NCGC00015882-28 |
NCGC00023141-02 |
NCGC00023141-04 |
NCGC00023141-05 |
NCGC00023141-06 |
NCGC00261749-01 |
6-(trifluoromethoxy)-2-aminobenzothiazole |
6-trifluoromethoxybenzodthiazol-2-amine |
BR164340 |
ST038494 |
ST068834 |
SBI-0051034.P002 |
2-Amino-6-(Trifluoromethoxy) Benzothiazole |
6-(Trifluoromethoxy)-2-amino-benzothiazole |
AB0012884 |
DB-030335 |
EU-0101064 |
FT-0611194 |
R1174 |
SW196805-4 |
EN300-23782 |
6-trifluoromethoxy-1,3-benzothiazol-2-ylamine |
C07937 |
D00775 |
J10184 |
J10441 |
VU0239571-11 |
744R225 |
Q415744 |
SR-01000002997-3 |
BRD-K21283037-001-02-5 |
BRD-K21283037-003-03-9 |
BRD-K21283037-003-06-2 |
F3282-0020 |
Z166605314 |
Rilutek|||Rilutor|||6-(Trifluoromethoxy)-2-benzothiazolamine |
Riluzole, United States Pharmacopeia (USP) Reference Standard |
2-Amino-6-(trifluoromethoxy)-1,3-benzothiazole;2-AMINO-6-(TRIFLUOROMETHOXY)BENZOTHIAZOLE |
Experimental Data
riluzole
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -22.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
riluzole
Statistics Data
riluzole
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -22.000000000000000 | 1 | 1 |
Statistics Data Visualization
riluzole
