Compound Summary
trolox
Compound Information
trolox
Compound Name: | trolox |
Compound CID: | 40634 |
Synonyms: | trolox 53188-07-1 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid TROLOX C 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid More... |
Iupac Name: | 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid |
InChI: | InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17) |
InChIKey: | GLEVLJDDWXEYCO-UHFFFAOYSA-N |
Canonical Smiles: | CC1=C(C2=C(CCC(O2)(C)C(=O)O)C(=C1O)C)C |
Isomeric Smiles: | CC1=C(C2=C(CCC(O2)(C)C(=O)O)C(=C1O)C)C |
Molecular Weight: | 250.29 |
Molecular Formula: | C14H18O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
trolox
Molecular Weight: | 250.29 |
Molecular Formula: | C14H18O4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 18 |
Complexity: | 343 |
Synonyms
trolox
| trolox | trolox |
|---|---|
trolox |
53188-07-1 |
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid |
TROLOX C |
3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid |
6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid |
2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl- |
MFCD00006846 |
56305-04-5 |
CHEBI:82625 |
(+/-)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid |
6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid |
6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromene-2-carboxylic acid |
6-hydroxy-2,5,7,8-tetramethyl-chromane-2-carboxylic acid |
EINECS 258-422-8 |
BRN 5052542 |
Trolox? |
Trolox® |
Trolox(TM) |
Prestwick_855 |
ACMC-20apju |
ACMC-1ATBW |
Prestwick0_000530 |
Prestwick1_000530 |
Prestwick2_000530 |
Prestwick3_000530 |
CHEMBL153 |
SCHEMBL3226 |
2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (+-)- |
Oprea1_727377 |
BSPBio_000519 |
MLS002153860 |
SPBio_002440 |
BPBio1_000571 |
DTXSID60866306 |
HMS1569J21 |
HMS2096J21 |
HMS2230A15 |
HMS3369E20 |
HMS3713J21 |
HMS3885K19 |
BCP16474 |
BBL103047 |
BDBM50359629 |
GEO-03688 |
s3665 |
SBB005933 |
STL556856 |
6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid |
AKOS015856256 |
CCG-207912 |
CS-8035 |
MCULE-8649288753 |
NCGC00179534-01 |
AS-30121 |
SMR001233218 |
ST057520 |
DB-052268 |
DB-071631 |
HY-101445 |
FT-0621156 |
FT-0770514 |
H0726 |
Q245489 |
SR-01000841227 |
SR-01000841227-2 |
BRD-A17846016-001-03-0 |
BRD-A17846016-001-07-1 |
6-hydroxy-2,5,7,8-tetramethychroman-2-carboxylic acid |
6-Hydroxy-2,5,7,8-tetramethyl-2-chromancarboxylic acid |
6-Hydroxy-2,5,7,8-tetramethyl-2-chromanecarboxylic acid # |
6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid |
(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)carboxylic acid |
(+/-)- 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid |
(+/-)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid |
(+/-)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, 97% |
(S)-(-)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLICACID |
3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzo-pyran-2-carboxylic Acid |
3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic Acid; |
6-hydroxy-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid |
Experimental Data
trolox
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 600.000000000000000 | umol/L | 8.870000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 579.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 200.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 116.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 3.000000000000000 | mM | 15.960000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 500.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 1.000000000000000 | mM | 18.010000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 2.900000000000000 | mM | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 600.000000000000000 | umol/L | 15.000000000000000 | 17.000000000000000 | 0.130000000000000 | S | N2 | 18755260 | Active | ||||
| Caenorhabditis elegans | 17.800000000000000 | 18.400000000000000 | 0.030000000000000 | 25.000000000000000 | 28.000000000000000 | 0.120000000000000 | NS | N2 | 17908557 | Inactive | |||
| Caenorhabditis elegans | 1.000000000000000 | mM | 14.000000000000000 | 19.000000000000000 | 0.360000000000000 | S | 18755260 | Active | |||||
| Caenorhabditis elegans | 3.000000000000000 | mM | 15.000000000000000 | 20.000000000000000 | 0.330000000000000 | S | N2 | 18755260 | Active | ||||
| Caenorhabditis elegans | 17.800000000000000 | 18.300000000000000 | 0.030000000000000 | 25.000000000000000 | 26.000000000000000 | 0.040000000000000 | NS | N2 | 17908557 | Inactive | |||
| Caenorhabditis elegans | 3.000000000000000 | mM | 12.000000000000000 | 17.000000000000000 | 0.420000000000000 | S | N2 | 18755260 | Active |
Experimental Data Visualization
trolox
Statistics Data
trolox
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.420000000000000 | 18.010000000000000 | 3 | 14 |
Statistics Data Visualization
trolox
