Compound Summary
tyrphostin AG-1478
Compound Information
tyrphostin AG-1478
Compound Name: | tyrphostin AG-1478 |
Compound CID: | 2051 |
Synonyms: | AG-1478 153436-53-4 Tyrphostin AG 1478 N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine 175178-82-2 More... |
Iupac Name: | N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine |
InChI: | InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20) |
InChIKey: | GFNNBHLJANVSQV-UHFFFAOYSA-N |
Canonical Smiles: | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC |
Isomeric Smiles: | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC |
Molecular Weight: | 315.75 |
Molecular Formula: | C16H14ClN3O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
tyrphostin AG-1478
Molecular Weight: | 315.75 |
Molecular Formula: | C16H14ClN3O2 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 22 |
Complexity: | 360 |
Synonyms
tyrphostin AG-1478
| tyrphostin AG-1478 | tyrphostin AG-1478 |
|---|---|
AG-1478 |
153436-53-4 |
Tyrphostin AG 1478 |
N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine |
175178-82-2 |
Tyrphostin AG-1478 |
4-(3-Chloroanilino)-6,7-dimethoxyquinazoline |
AG1478 |
AG 1478 |
4-Quinazolinamine, N-(3-chlorophenyl)-6,7-dimethoxy- |
AG-1478 (Tyrphostin AG-1478) |
tyrphostin AG1478 |
AG-1478 free base |
SUH0SEZ9HY |
NSC-693255 |
CHEMBL7917 |
N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine |
CHEBI:75404 |
Tyrphostin AG-1478;NSC 693255 |
(3-Chlorophenyl)(6,7-dimethoxyquinazolin-4-yl)amine |
BRD6408 |
BRD-6408 |
SR-01000076156 |
NSC693255 |
Tocris-1276 |
tyrphostin-AG-1478 |
UNII-SUH0SEZ9HY |
BiomolKI_000018 |
Maybridge1_004001 |
Lopac-T-4182 |
BiomolKI2_000028 |
CBiol_002058 |
Lopac0_001127 |
Oprea1_653581 |
SCHEMBL93838 |
BSPBio_001390 |
KBioGR_000110 |
KBioSS_000110 |
MLS006012026 |
BDBM3532 |
GTPL4862 |
N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine |
DTXSID0051447 |
BCBcMAP01_000035 |
HMS552N19 |
KBio2_000110 |
KBio2_002678 |
KBio2_005246 |
KBio3_000219 |
KBio3_000220 |
Bio1_000344 |
Bio1_000833 |
Bio1_001322 |
Bio2_000110 |
Bio2_000590 |
HMS1361F12 |
HMS1791F12 |
HMS1989F12 |
HMS3229O03 |
HMS3263B15 |
HMS3656B19 |
HMS3672E11 |
ZINC116937 |
BCP07988 |
BCP15152 |
EX-A1236 |
Tyrphostin AG 1478, >=98% |
Tox21_303781 |
Tox21_501127 |
BBL101047 |
CCG-52663 |
MFCD00270914 |
s2728 |
STL554841 |
AKOS002350880 |
AG-1478 - Tyrphostin AG-1478 |
CS-1606 |
LP01127 |
NSC 693255 |
SB19361 |
SDCCGSBI-0051095.P003 |
IDI1_033860 |
NCGC00016017-01 |
NCGC00016017-02 |
NCGC00016017-03 |
NCGC00016017-04 |
NCGC00016017-05 |
NCGC00016017-06 |
NCGC00016017-07 |
NCGC00016017-08 |
NCGC00016017-09 |
NCGC00016017-20 |
NCGC00025093-01 |
NCGC00025093-02 |
NCGC00025093-03 |
NCGC00025093-04 |
NCGC00025093-05 |
NCGC00261812-01 |
NCGC00357072-01 |
AC-32828 |
GK 03499 |
HY-13524 |
NCI60_033425 |
SMR001456495 |
DB-026463 |
CAS-175178-82-2 |
EU-0101127 |
FT-0643504 |
FT-0643682 |
SW219714-1 |
T2944 |
EC-000.2540 |
6,7-dimethoxy-4-(3-chloroanilino)quinazoline |
A24890 |
T 4182 |
11N-812 |
A811809 |
AG-1478;Tyrphostin AG-1478; NSC 693255 |
CU-00000000399-1 |
J-011074 |
J-519544 |
SR-01000076156-1 |
SR-01000076156-4 |
SR-01000076156-7 |
AG 1478 - CAS 175178-82-2 |
BRD-K68336408-001-02-6 |
BRD-K68336408-003-02-2 |
Q27074338 |
COC1=C(OC)C=C2C(NC3=CC(Cl)=CC=C3)=NC=NC2=C1 |
B0084-209186 |
0TO |
Experimental Data
tyrphostin AG-1478
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 60.480000000000000 | S | N2 | 30970250 | Active | ||||||
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 13.730000000000000 | S | N2 | 30970250 | Active |
Experimental Data Visualization
tyrphostin AG-1478
Statistics Data
tyrphostin AG-1478
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 60.480000000000000 | 1 | 2 |
Statistics Data Visualization
tyrphostin AG-1478
